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Tag: Genetics, Genomics and Cell Biology of Infection

  1. Gerald Duhamel, Biomedical Sciences

    Gerald Duhamel

    My research is focused on the eukaryotic cell DNA damage response (DDR) to a novel bacterial genotoxin called cytolethal distending toxin (CDT) within the context of intestinal disease of human and animals. I also have extensive experience in the development and assessment of laboratory animal[...]
  2. Andrew Clark, Molecular Biology & Genetics

    Andrew Clark

    We study the molecular evolution and population genetics of the immune system in Drosophila and other insects, specifically focusing on comparative genomics and transcriptional regulation of the immune response. We also explore host genetic variation in microbiome composition and function in a large human twin study and[...]
  3. Yung-Fu Chang, Population Medicine and Diagnostic Sciences

    Yung-Fu Chang

    My research focuses on the pathogenesis of bacterial diseases and vaccine protection mechanisms.  My lab is working on the interaction of host receptors and virulence factors of C. difficile (toxins), Leptospira spp, and F. nucleatum (adhesins).  We are also working on the mucosa immunity against F. nucleatum and M. avium subsp. paratuberculosis using outer membrane vesicle[...]
  4. Gary Whittaker, Microbiology and Immunology

    Gary Whittaker

    My lab has a broad interest in the structure and function of viral envelope proteins, and how genomic mutations lead to changes in the envelope proteins and control viral pathogenesis. We primarily study influenza viruses of humans and animals, and coronaviruses, principally, SARS-CoV, MERS-CoV and[...]
  5. Brian VanderVen, Microbiology and Immunology

    Brian VanderVen

    We study how M.tuberculosis is capable of surviving within humans for decades in the face of a fully competent immune response.  Our focus is primarily on the bacterial pathways, innate immunity, and the evolution of bacterial drug resistance in mammalian hosts.
  6. Gillian Turgeon, Plant Pathology and Plant-Microbe Biology

    Gillian Turgeon

    The Turgeon lab works on mechanisms of fungal virulence to plants with particular emphasis on the roles of fungal secondary metabolites, iron and oxidative stress. Classical genetic, molecular genetic, and genomic approaches are used.
  7. Jeongmin Song, Microbiology and Immunology

    Jeongmin Song

    The unifying themes of my ongoing research program are seeking to understand the underlying mechanisms that control the pathogenesis and disease associated with bacterial infections, as well as developing control strategies for the bacteria or its associated disease. The main focus for the past years[...]
  8. Christine Smart, Plant Pathology and Plant-Microbe Biology

    Christine Smart

    Two main areas of study in the Smart lab include identifying genes in bacterial pathogens that enable movement within a plant, and understanding the population diversity of rapidly reproducing oomycete pathogens. These studies enhance our knowledge of pathogen virulence determinants and further elucidate how plants[...]
  9. Brian Rudd, Microbiology and Immunology

    Brian Rudd

    The Rudd lab is interested in how microbes alter immune development and how the adaptive immune system protects the host against acute and chronic pathogens.
  10. Joseph Peters, Microbiology

    Joe Peters

    The Peters lab studies microbial evolution via mobile genetic elements. We are interested in how mobile elements evolve new functions within host-associated bacteria. Students in the lab will develop skills in bioinformatics, molecular genetics, and biochemistry. An example student project is using sequencing data to[...]