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Research Area: Viruses

  1. Avery August

    The August lab is interested in infection-based and environment signals that trigger inflammation. We are particularly interested in signals regulated by the Tec family kinases, and how they regulate activation of cells such as mast cells and T cells to drive their differentiation and production[...]
  2. Gary Blissard, Boyce Thompson Institute

    Gary Blissard

    The Blissard lab addresses fundamental questions on the biology and pathology of virus-insect interactions. A primary focus is the study of viral envelope glycoproteins and their interactions with host insect cells and cell proteins during viral entry and egress. Another focus are is understanding the[...]
  3. Nicholas Buchon, Department of Entomology

    Nicolas Buchon

    The Buchon lab focuses on the impact of pathogens and the microbiota on body homeostasis. We use systemic infection as a model for septicemia, and the gut response to infection as a model for mucosal immunity. Genomic and genetic approaches allow us to characterize new[...]
  4. Dan Buckley, Soil and Crop Sciences

    Dan Buckley

    My research program explores soil microbiome dynamics and their impacts on ecosystem health, the plants we grow, the water we drink, and the air we breath. We use genomic approaches to examine the ecological and evolutionary mechanisms that regulate microbial diversity and its impact on[...]
  5. Clare Casteel, PPPMB

    Clare Casteel

    Numerous studies demonstrate that vector-borne pathogens influence host characteristics, resulting in altered host-vector interactions and enhanced transmission. We seek to determine the molecular mechanisms that underlie this phenomenon and use this knowledge to develop innovative control strategies using genetic and biochemical approaches. Current focuses are[...]
  6. Yung-Fu Chang, Population Medicine and Diagnostic Sciences

    Yung-Fu Chang

    My research focuses on the pathogenesis of bacterial diseases and vaccine protection mechanisms.  My lab is working on the interaction of host receptors and virulence factors of C. difficile (toxins), Leptospira spp, and F. nucleatum (adhesins).  We are also working on the mucosa immunity against F. nucleatum and M. avium subsp. paratuberculosis using outer membrane vesicle[...]
  7. Andrew Clark, Molecular Biology & Genetics

    Andrew Clark

    We study the molecular evolution and population genetics of the immune system in Drosophila and other insects, specifically focusing on comparative genomics and transcriptional regulation of the immune response. We also explore host genetic variation in microbiome composition and function in a large human twin study and[...]
  8. Shaun Cross, CIHMID Postdoc

    Shaun Cross

    Shaun’s research focuses on the development of sequencing technologies to better elucidate host-virus interactions using enteric viruses (rotaviruses and mammalian orthroreoviruses). By augmenting spatial transcriptomic sequencing platforms, he aims to understand how the host reacts to viral infections across space and time and how these[...]
  9. Andre Dhondt

    The Dhondt lab has studied the bacterial disease mycoplasmal conjunctivitis since it emerged in birds around 1994. We currently study effects of coinfection by combining studies of Mycoplasmal gallisepticum, haemosporidian parasites and other pathogens in the same individual. Students participate in both field work (trapping,[...]
  10. Gerald Duhamel, Biomedical Sciences

    Gerald Duhamel

    My research is focused on the eukaryotic cell DNA damage response (DDR) to a novel bacterial genotoxin called cytolethal distending toxin (CDT) within the context of intestinal disease of human and animals. I also have extensive experience in the development and assessment of laboratory animal[...]