Tag: Genetics, Genomics and Cell Biology of Infection

My lab has a broad interest in the structure and function of viral envelope proteins, and how genomic mutations lead to changes in the envelope proteins and control viral pathogenesis. We primarily study influenza viruses of humans and animals, and coronaviruses, principally, SARS-CoV, MERS-CoV and[...]

We study how M.tuberculosis is capable of surviving within humans for decades in the face of a fully competent immune response.  Our focus is primarily on the bacterial pathways, innate immunity, and the evolution of bacterial drug resistance in mammalian hosts.

The Turgeon lab works on mechanisms of fungal virulence to plants with particular emphasis on the roles of fungal secondary metabolites, iron and oxidative stress. Classical genetic, molecular genetic, and genomic approaches are used.

The unifying themes of my ongoing research program are seeking to understand the underlying mechanisms that control the pathogenesis and disease associated with bacterial infections, as well as developing control strategies for the bacteria or its associated disease. The main focus for the past years[...]

Two main areas of study in the Smart lab include identifying genes in bacterial pathogens that enable movement within a plant, and understanding the population diversity of rapidly reproducing oomycete pathogens. These studies enhance our knowledge of pathogen virulence determinants and further elucidate how plants[...]

The Rudd lab is interested in how microbes alter immune development and how the adaptive immune system protects the host against acute and chronic pathogens.

The Peters lab studies microbial evolution via mobile genetic elements. We are interested in how mobile elements evolve new functions within host-associated bacteria. Students in the lab will develop skills in bioinformatics, molecular genetics, and biochemistry. An example student project is using sequencing data to[...]

We study the mechanisms underlying ecological interactions between fungi and bacteria.  Student projects will focus on current work to characterize the bacteria associated with mycorrhizal fungi in poorly studied desert habitats in California and Israel. Students will learn culture and microscopy techniques, and phylogenetic analysis.

My laboratory studies viruses, with a particular focus on viruses that have jumped into new hosts to cause epidemics of disease. One model we study is canine parvovirus, which is a cat virus that transferred into dogs in the mid-1970s and subsequently caused a global[...]

The Parker lab uses the mammalian orthoreovirus model system and other human viruses to study virus-host interactions at the molecular and cellular level. Current projects are focused on the mechanisms viruses use to overcome translational repression and optimize translation of viral mRNAs, as well as[...]