Tag: Bacteria

The John Helmann lab has a new paper out, “A regulatory pathway that selectively up-regulates elongasome function in the absence of class A PBPs” in eLife.  LINK TO PAPER: https://pubmed.ncbi.nlm.nih.gov/32897856/

The long-term goals served by this project are mechanistic understanding of plant disease and development of broadly effective and durable means of control. The project seeks to structurally and functionally characterize a pathogen-activated host gene that plays a critical role in disease in a major crop species, and to ascertain the potential of strategies to […]

The Chang lab conducts research at the interface of chemical biology, microbiology, and immunology. Our research is focused on understanding chemical communication between the gut microbiome and the host immune system.  Using both chemical and biological approaches, we develop novel chemical tools to understand 1) the metabolism of the gut microbiome and 2) important pathways […]

The intestinal epithelium faces unique challenges as it is constantly exposed to the passage of ingested material including food, bacteria and xenobiotics. To maintain tissue function, the intestinal epithelium is undergoing continuous renewal mediated by intestinal stem cells (ISCs). ISC proliferation and differentiation are constantly adapted both to the microbes present and to the gut […]

Development of broadly neutralizing antibodies to influenza using a novel bacterial outer membrane vesicle platform: The Leifer and Putnam labs have an ongoing collaboration to use innovative engineering techniques develop, test, and understand the underlying immunological mechanisms of new vaccine adjuvant bacterial outer membrane vesicle platforms. We are interested in postdoctoral candidates proposing to take […]

The Hendry lab uses experimental and -omics approaches to understand the impact of host interactions on bacterial ecology and evolution, as well as how microbes influence hosts. Research in the lab focuses on a variety of systems, particularly insect and plant associated bacteria. Our interdisciplinary group encompasses broad interests within microbiology, evolution, and ecology and […]

The Pawlowska Lab studies interactions between fungi and bacteria using several model systems. Potential projects involve: (1) dissecting the mechanisms of innate immunity in fungi, (2) evaluating the impact of bacteriome on phenotypic diversity of fungi, and (3) examining the role of common mycorrhizal networks in plant microbiome assembly.

The Moreau lab focuses on the symbiotic factors that drive speciation, adaptation, and evolutionary diversification.  Much of the research in the lab focuses on the potential co-evolution of ants and their gut-associated bacteria to understand the diversity and putative function of host-associated microbes.  By coupling this information with data on diet, trophic ecology, evolutionary history […]

The Hendry lab studies the evolution and ecology of bacteria interacting with animal hosts, particularly insects. Study systems include both pathogenic interactions of bacteria with agriculturally important insects and mutualistic interactions where bacterial symbionts influence insect ecology and evolution. There are several undergraduate research opportunities in the lab using techniques in microbiology, ecological experiments, and […]

The Helmann lab investigates adaptation to stress using Bacillus subtilis as a model organism. One project focuses on the roles of alternative sigma factors and other regulators in controlling cell envelope stress responses. These studies support our ongoing work on the molecular mechanisms of antibiotic resistance. A second major research effort is directed at metal ion homeostasis. Metal regulation plays […]