Tag: Bacteria

The Martin lab studies the molecular bases of bacterial infection processes and the plant immune system. Our research focuses on speck disease caused by the bacterial pathogen Pseudomonas syringae pv. tomato. We use diverse experimental methods in biochemistry, bioinformatics, cell biology, forward and reverse genetics, genomics, molecular[...]

The Leifer lab investigates how the immune system detects and initiates inflammatory responses to microbes. We focus on innate immune macrophages and the regulatory mechanisms that control inflammation through Toll-like receptors (TLRs).

The goal of the Kao-Kniffin Lab is to understand the functional role of rhizosphere microbiomes in modifying plant traits. The rhizosphere harbors a tremendous diversity of soil microorganisms that enhance or inhibit plant growth. We are applying concepts in ecology and evolution to assemble microbiomes[...]

We study how lipids mediate host-microbiome interactions.   A potential student project in the lab involves using techniques developed in the lab to identify novel interactions of saturated fatty acids with the gut microbiome and developing advanced techniques in anaerobic microbial genetics to determine the consequences[...]

We use Bacillus subtilis as a model system to characterize the bacterial stress responses elicited by metal ion limitation and excess during infection, and by host-produced antibiotics that interfere with integrity of the cell envelope. The resulting insights are relevant for understanding the mechanisms that allow bacterial[...]

We study how bacteria respond to and survive stressful conditions, particularly damage to the cell envelope. Students in the Doerr lab learn techniques ranging from microscopy and image analysis to molecular biology. The lab is very active with undergraduate research and has extensive experience in[...]

Our research focuses primarily on three areas: We develop activity-based probes to understand the metabolic activity catalyzed by the gut microbiome during different disease states. We also characterize the small-molecule metabolites produced by the gut microbiota that regulate inflammation during inflammatory diseases and host defense[...]

My research program explores soil microbiome dynamics and their impacts on ecosystem and plant health. Students will use genomics and culture-based experiments to understand how soil bacteria response to plant root exudates. They will gain skills in microbiology and bioinformatics, and learn concepts in community[...]

The Buchon lab focuses on the impact of pathogens and the microbiota on body homeostasis. We use systemic infection as a model for septicemia, and the gut response to infection as a model for mucosal immunity. Genomic and genetic approaches allow us to characterize new[...]

Our research centers on crop diseases caused by bacteria in the genus Xanthomonas, focusing on TAL effector proteins injected by the bacteria to manipulate expression of specific host genes important for disease development. Our lab also studies plant disease resistance mechanisms triggered by TAL effectors[...]