Tag: Animal Hosts

Our research focuses primarily on three areas: We develop activity-based probes to understand the metabolic activity catalyzed by the gut microbiome during different disease states. We also characterize the small-molecule metabolites produced by the gut microbiota that regulate inflammation during inflammatory diseases and host defense[...]

The Buchon lab focuses on the impact of pathogens and the microbiota on body homeostasis. We use systemic infection as a model for septicemia, and the gut response to infection as a model for mucosal immunity. Genomic and genetic approaches allow us to characterize new[...]

The Blissard lab addresses fundamental questions on the biology and pathology of virus-insect interactions. A primary focus is the study of viral envelope glycoproteins and their interactions with host insect cells and cell proteins during viral entry and egress. Another focus are is understanding the[...]

The Brito lab has published a paper in Nature in collaboration with the De Vlaminck Lab; “Highly multiplexed spatial mapping of microbial communities.” PAPER: https://www.nature.com/articles/s41586-020-2983-4

I study how microbes in the human microbiome are transmitted among individuals, using a wide range of approached including shotgun metagenomics of microbiome communities, culture-based methods, and single-cell analyses. Another main focus is horizontal transmission of genes between members of the microbiome, specifically focusing on[...]

The August lab is interested in infection-based and environment signals that trigger inflammation. We are particularly interested in signals regulated by the Tec family kinases, and how they regulate activation of cells such as mast cells and T cells to drive their differentiation and production[...]

Information for non-Cornell students on the NSF-funded Microbial Friends & Foes REU; and information for current Cornell students on CIHMID’s URE.

Opportunistic pathogens can subvert infection barriers (e.g., host immune functions and nutrient limitations) and switch from peaceful commensal to potentially lethal pathogen. The factors promoting either outcome are unknown, but must be shaped by dynamic physiological interactions between host and pathogen. This project aims to determine key factors at the host-pathogen interface that mediate the […]

New paper out, produced with David Bucholz, Microbiolgy & Immunology, CVM. “Finding proteases that make cells go viral”, J Biol Chem. 2020 Aug. PAPER:     https://pubmed.ncbi.nlm.nih.gov/32817125/

Our research explores the impact of host behavior and nutritional needs on the evolution of intestinal symbionts. Current projects include the study of signals that coordinate the physiology and development of intestinal bacteria with the feeding activity of their host. We are also interested in[...]