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Research Area: Animal Hosts

  1. Marian Schmidt, Microbiology

    Marian Schmidt

    Climate change dramatically impacts freshwater ecosystems, which are becoming warmer, more acidic, and nutrient rich. The collective influence of the microbial inhabitants of these ecosystems, despite their tiny size, can have an immense impact on water quality. However, we lack fundamental knowledge on the ecology[...]
  2. Deborah Fowell, Microbiology & Immunology

    Deborah Fowell

    We are actively engaged in defining the signals that enable effector T cells to ‘find’ areas of infection and damage within inflamed tissues. We utilize intravital multiphoton microscopy and optogenetic tools to visualize and manipulate effector CD4+ T cells in situ. These approaches have revealed extrinsic[...]
  3. Brandon Hollingsworth, CIHMID Postdoctoral Fellow

    Brandon Hollingsworth

    I am interested in finding better ways of controlling the mosquito Aedes aegypti, the main vector of dengue and Zika viruses. Specifically, I am interested in determining how they move through their environment and the effect that has on different control strategies. The mosquito virome, the[...]
  4. Kelsi Sandoz, Population Medicine and Diagnostic Sciences

    Kelsi Sandoz

    Research in my lab probes the environmental, structural and physiological basis of bacterial survival. The majority of earth’s microbes exist in a non-growing, surival state, making it important to better understand the mechanisms underpinning this physiological state. We primarily use the environmental zoonotic pathogen, Coxiella burnetii (causative agent[...]
  5. Janelle Veazey, CIHMID Postdoctoral Fellow

    Janelle Veazey

    Janelle’s research project aims to understand how diet affects the microbiome, and how these diet-dependent microbiome changes affect the immune system- particularly CD8+ T cells. Her work also uses flow cytometry and sequencing to look at how diet and microbiome changes in early life affects[...]
  6. Gabrielle Le-Bury

    Macrophages are susceptible to HIV-1 infection and are resistant to virally-induced cell death. Alveolar macrophages (AM) in particular are known to be extremely long-lived and self-renewing, and have been shown to be both permissive to HIV-1 infection and persist in the face of Anti-Retroviral Therapy[...]
  7. Shaun Cross, CIHMID Postdoc

    Shaun Cross

    Shaun’s research focuses on the development of sequencing technologies to better elucidate host-virus interactions using enteric viruses (rotaviruses and mammalian orthroreoviruses). By augmenting spatial transcriptomic sequencing platforms, he aims to understand how the host reacts to viral infections across space and time and how these[...]
  8. Iris Holmes, CIHMID Postdoc Fellow

    Iris Holmes

    Iris explores the ways that vertebrate hosts cope with infections from the diverse community of parasites they encounter throughout their lives. Specifically, she looks at signatures of selection on the immune genes of lizards, and correlate those signatures with the lizard’s parasite community. Iris is[...]
  9. Frank Schroeder, Boyce Thompson Institute

    Frank Schroeder

    Our research is directed at characterizing structures and biological function of biogenic small molecules (BSMs) that regulate development and immune responses in plants and animals and serve important functions with associated microbiota. Using comparative metabolomic approaches we have engaged in a comprehensive effort to characterize[...]
  10. Luis Schang, Microbiology and Immunology

    Luis Schang

    Dr. Schang uses small molecules with drug-like properties to probe the ways viruses cause infections. He is most interested in finding common features among the many viruses that cause disease in animals or humans, including how they enter cells and how they replicate and cause[...]