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Tag: Veterinary/Clinical Research

  1. Hector Aguilar-Carreno

    The main focus of our research program is to elucidate key mechanistic components in enveloped viruses and their host cells that: 1) mediate viral entry into cells, 2) elicit cell immune responses, and 3) mediate viral egress from cells. These studies are leading to the[...]
  2. Nicholas Buchon, Department of Entomology

    Nicolas Buchon

    The Buchon lab focuses on the impact of pathogens and the microbiota on body homeostasis. We use systemic infection as a model for septicemia, and the gut response to infection as a model for mucosal immunity. Genomic and genetic approaches allow us to characterize new[...]
  3. Yung-Fu Chang, Population Medicine and Diagnostic Sciences

    Yung-Fu Chang

    My research focuses on the pathogenesis of bacterial diseases and vaccine protection mechanisms.  My lab is working on the interaction of host receptors and virulence factors of C. difficile (toxins), Leptospira spp, and F. nucleatum (adhesins).  We are also working on the mucosa immunity against F. nucleatum and M. avium subsp. paratuberculosis using outer membrane vesicle[...]
  4. Andrew Clark, Molecular Biology & Genetics

    Andrew Clark

    We study the molecular evolution and population genetics of the immune system in Drosophila and other insects, specifically focusing on comparative genomics and transcriptional regulation of the immune response. We also explore host genetic variation in microbiome composition and function in a large human twin study and[...]
  5. Andre Dhondt

    The Dhondt lab has studied the bacterial disease mycoplasmal conjunctivitis since it emerged in birds around 1994. We currently study effects of coinfection by combining studies of Mycoplasmal gallisepticum, haemosporidian parasites and other pathogens in the same individual. Students participate in both field work (trapping,[...]
  6. Tobias Dörr, Cell & Molecular Biology

    Tobias Dörr

    My group studies cell envelope stress responses of Gram-negative pathogens. We are defining regulatory pathways and functional networks of enzymes involved in cell wall degradation, modification and synthesis as well as factors required for upholding outer membrane barrier function. We seek to understand these processes[...]
  7. Gerald Duhamel, Biomedical Sciences

    Gerald Duhamel

    My research is focused on the eukaryotic cell DNA damage response (DDR) to a novel bacterial genotoxin called cytolethal distending toxin (CDT) within the context of intestinal disease of human and animals. I also have extensive experience in the development and assessment of laboratory animal[...]
  8. Deborah Fowell, Microbiology & Immunology

    Deborah Fowell

    We are actively engaged in defining the signals that enable effector T cells to ‘find’ areas of infection and damage within inflamed tissues. We utilize intravital multiphoton microscopy and optogenetic tools to visualize and manipulate effector CD4+ T cells in situ. These approaches have revealed extrinsic[...]
  9. Laura Harrington, Entomolgy

    Laura Harrington

    My research focuses on the biology, ecology and behavior of mosquitoes that transmit human diseases such as dengue fever, West Nile virus and malaria. I have developed methods for studying blood feeding patterns, survival and longevity, mating behavior and feeding behavior of mosquitoes in both[...]
  10. The impact of interindividual variation in oral and gut microbiomes on host health

    The Poole Lab studies the causes and effects of human microbiome variation with the goal of manipulating microbes to improve human health. We want to know why individuals respond differently to the same dietary intervention in order to develop precision nutrition protocols for the prevention and treatment of metabolic disorders. Our resources include, but are not […]