Tag: Genomics and Cell Biology of Infection

The Bogdanove lab’s research centers on the development of broad-spectrum, durable disease resistance in crop plants with a focus on diseases caused by bacteria that deploy host DNA binding proteins called TAL effectors. We also continue to be interested in the use of TAL effectors as customizable DNA targeting tools for applications such as targeted […]

Antibiotic treatment failure is an increasingly widespread burden on human health that poses one of the most significant threats to planetary life. Treatment failure is often due to the development of antibiotic resistance. A complete comprehension of the factors that promote the development, and particularly the dissemination, of antibiotic resistance is still lacking. Nonetheless, evidence […]

Iris explores the ways that vertebrate hosts cope with infections from the diverse community of parasites they encounter throughout their lives. Specifically, she looks at signatures of selection on the immune genes of lizards, and correlate those signatures with the lizard’s parasite community. Iris is[...]

Information for non-Cornell students on the NSF-funded Microbial Friends & Foes REU; and information for current Cornell students on CIHMID’s URE.

Opportunistic pathogens can subvert infection barriers (e.g., host immune functions and nutrient limitations) and switch from peaceful commensal to potentially lethal pathogen. The factors promoting either outcome are unknown, but must be shaped by dynamic physiological interactions between host and pathogen. This project aims to determine key factors at the host-pathogen interface that mediate the […]