Tag: Genomics and Cell Biology of Infection

The Heck lab deciphers molecular mechanisms regulating insect transmission of plant pathogens and uses this knowledge to create practical solutions that mitigate vector-borne diseases in agriculture. We use a combination of computational and wet-lab approaches to study vector-pathogen-plant interactions. Students will receive training at the intersections of computational biology, plant pathology, entomology, microbiology, genetic engineering […]

The Bogdanove lab’s research centers on the development of broad-spectrum, durable disease resistance in crop plants with a focus on diseases caused by bacteria that deploy host DNA binding proteins called TAL effectors. We also continue to be interested in the use of TAL effectors as customizable DNA targeting tools for applications such as targeted […]

Antibiotic treatment failure is an increasingly widespread burden on human health that poses one of the most significant threats to planetary life. Treatment failure is often due to the development of antibiotic resistance. A complete comprehension of the factors that promote the development, and particularly the dissemination, of antibiotic resistance is still lacking. Nonetheless, evidence […]

Information for non-Cornell students on the NSF-funded Microbial Friends & Foes REU; and information for current Cornell students on CIHMID’s URE.

Opportunistic pathogens can subvert infection barriers (e.g., host immune functions and nutrient limitations) and switch from peaceful commensal to potentially lethal pathogen. The factors promoting either outcome are unknown, but must be shaped by dynamic physiological interactions between host and pathogen. This project aims to determine key factors at the host-pathogen interface that mediate the […]