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Research Area: Veterinary/Clinical Research

  1. Hector Aguilar-Carreno

    The main focus of our research program is to elucidate key mechanistic components in enveloped viruses and their host cells that: 1) mediate viral entry into cells, 2) elicit cell immune responses, and 3) mediate viral egress from cells. These studies are leading to the[...]
  2. Nicholas Buchon, Department of Entomology

    Nicolas Buchon

    The Buchon lab focuses on the impact of pathogens and the microbiota on body homeostasis. We use systemic infection as a model for septicemia, and the gut response to infection as a model for mucosal immunity. Genomic and genetic approaches allow us to characterize new[...]
  3. Yung-Fu Chang, Population Medicine and Diagnostic Sciences

    Yung-Fu Chang

    My research focuses on the pathogenesis of bacterial diseases and vaccine protection mechanisms.  My lab is working on the interaction of host receptors and virulence factors of C. difficile (toxins), Leptospira spp, and F. nucleatum (adhesins).  We are also working on the mucosa immunity against F. nucleatum and M. avium subsp. paratuberculosis using outer membrane vesicle[...]
  4. Andrew Clark, Molecular Biology & Genetics

    Andrew Clark

    We study the molecular evolution and population genetics of the immune system in Drosophila and other insects, specifically focusing on comparative genomics and transcriptional regulation of the immune response. We also explore host genetic variation in microbiome composition and function in a large human twin study and[...]
  5. Andre Dhondt

    The Dhondt lab has studied the bacterial disease mycoplasmal conjunctivitis since it emerged in birds around 1994. We currently study effects of coinfection by combining studies of Mycoplasmal gallisepticum, haemosporidian parasites and other pathogens in the same individual. Students participate in both field work (trapping,[...]
  6. Tobias Dörr, Cell & Molecular Biology

    Tobias Dörr

    My group studies cell envelope stress responses of Gram-negative pathogens. We are defining regulatory pathways and functional networks of enzymes involved in cell wall degradation, modification and synthesis as well as factors required for upholding outer membrane barrier function. We seek to understand these processes[...]
  7. Gerald Duhamel, Biomedical Sciences

    Gerald Duhamel

    My research is focused on the eukaryotic cell DNA damage response (DDR) to a novel bacterial genotoxin called cytolethal distending toxin (CDT) within the context of intestinal disease of human and animals. I also have extensive experience in the development and assessment of laboratory animal[...]
  8. Iris Holmes, CIHMID Postdoc Fellow

    Iris Holmes

    Iris explores the ways that vertebrate hosts cope with infections from the diverse community of parasites they encounter throughout their lives. Specifically, she looks at signatures of selection on the immune genes of lizards, and correlate those signatures with the lizard’s parasite community. Iris is[...]
  9. Elizabeth Johnson, Nutritional Sciences

    Elizabeth Johnson

    Our lab is interested in understanding mechanisms of lipid dependent host-microbe interactions and how these interactions influence human health. We use techniques in high-throughput sequencing, mass spectrometry based lipidomics, and general molecular biology to address these topics.
  10. Daniel Klessig, Boyce Thompson Institute

    Daniel Klessig

    Our research is focused on understanding how plants protect themselves against microbial pathogens at molecular and cellular levels. Major goals are to determine the mechanisms of salicylic acid (SA) activation and regulation of the plant’s immune responses, and to identify new targets or aspirin (acetyl[...]