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Research Area: Genetics, Genomics and Cell Biology of Infection

  1. Marian Schmidt, Microbiology

    Marian Schmidt

    Climate change dramatically impacts freshwater ecosystems, which are becoming warmer, more acidic, and nutrient rich. The collective influence of the microbial inhabitants of these ecosystems, despite their tiny size, can have an immense impact on water quality. However, we lack fundamental knowledge on the ecology[...]
  2. Deborah Fowell, Microbiology & Immunology

    Deborah Fowell

    We are actively engaged in defining the signals that enable effector T cells to ‘find’ areas of infection and damage within inflamed tissues. We utilize intravital multiphoton microscopy and optogenetic tools to visualize and manipulate effector CD4+ T cells in situ. These approaches have revealed extrinsic[...]
  3. Brandon Hollingsworth, CIHMID Postdoctoral Fellow

    Brandon Hollingsworth

    I am interested in finding better ways of controlling the mosquito Aedes aegypti, the main vector of dengue and Zika viruses. Specifically, I am interested in determining how they move through their environment and the effect that has on different control strategies. The mosquito virome, the[...]
  4. Heather Feaga, Microbiology

    Heather Feaga

    The Feaga lab is focused on how bacteria maintain protein synthesis capacity under stress. We aim to identify factors that interact with the ribosome and prevent stalling, and to understand the impact of ribosome stalling on cell physiology. In particular, we are interested in how[...]
  5. Janelle Veazey, CIHMID Postdoctoral Fellow

    Janelle Veazey

    Janelle’s research project aims to understand how diet affects the microbiome, and how these diet-dependent microbiome changes affect the immune system- particularly CD8+ T cells. Her work also uses flow cytometry and sequencing to look at how diet and microbiome changes in early life affects[...]
  6. Lori Huberman

    Fungi are responsible for devastating crop infestations that threaten global food supplies and diseases that result in the deaths of hundreds of thousands of individuals each year. We use genetic and genomic techniques spanning from classical molecular biology to high-throughput functional genomics to understand how[...]
  7. Jon Sanders

    Why do some gut bacteria stick to one host species, while others seem to hop around freely between them? What changes in their genomes when they move between hosts? And how can we begin to develop the data and tools we need to study these[...]
  8. Shaun Cross, CIHMID Postdoc

    Shaun Cross

    Shaun’s research focuses on the development of sequencing technologies to better elucidate host-virus interactions using enteric viruses (rotaviruses and mammalian orthroreoviruses). By augmenting spatial transcriptomic sequencing platforms, he aims to understand how the host reacts to viral infections across space and time and how these[...]
  9. Iris Holmes, CIHMID Postdoc Fellow

    Iris Holmes

    Iris explores the ways that vertebrate hosts cope with infections from the diverse community of parasites they encounter throughout their lives. Specifically, she looks at signatures of selection on the immune genes of lizards, and correlate those signatures with the lizard’s parasite community. Iris is[...]
  10. Frank Schroeder, Boyce Thompson Institute

    Frank Schroeder

    Our research is directed at characterizing structures and biological function of biogenic small molecules (BSMs) that regulate development and immune responses in plants and animals and serve important functions with associated microbiota. Using comparative metabolomic approaches we have engaged in a comprehensive effort to characterize[...]