Tag: Microbiota and Microbiomes
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Clare Casteel
Numerous studies demonstrate that vector-borne pathogens influence host characteristics, resulting in altered host-vector interactions and enhanced transmission. We seek to determine the molecular mechanisms that underlie this phenomenon and use this knowledge to develop innovative control strategies using genetic and biochemical approaches. Current focuses are[...] -
Dan Buckley
My research program explores soil microbiome dynamics and their impacts on ecosystem and plant health. Students will use genomics and culture-based experiments to understand how soil bacteria response to plant root exudates. They will gain skills in microbiology and bioinformatics, and learn concepts in community[...] -
Nicolas Buchon
The Buchon lab focuses on the impact of pathogens and the microbiota on body homeostasis. We use systemic infection as a model for septicemia, and the gut response to infection as a model for mucosal immunity. Genomic and genetic approaches allow us to characterize new[...] -
Adam Bogdanove
Our research centers on crop diseases caused by bacteria in the genus Xanthomonas, focusing on TAL effector proteins injected by the bacteria to manipulate expression of specific host genes important for disease development. Our lab also studies plant disease resistance mechanisms triggered by TAL effectors[...] -
Brito lab: HIPR-FISH paper in Nature
The Brito lab has published a paper in Nature in collaboration with the De Vlaminck Lab; “Highly multiplexed spatial mapping of microbial communities.” PAPER: https://www.nature.com/articles/s41586-020-2983-4
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Ilana Brito
I study how microbes in the human microbiome are transmitted among individuals, using a wide range of approached including shotgun metagenomics of microbiome communities, culture-based methods, and single-cell analyses. Another main focus is horizontal transmission of genes between members of the microbiome, specifically focusing on[...] -
Avery August
The August lab is interested in infection-based and environment signals that trigger inflammation. We are particularly interested in signals regulated by the Tec family kinases, and how they regulate activation of cells such as mast cells and T cells to drive their differentiation and production[...] -
Undergraduate Research Programs
Information for non-Cornell students on the NSF-funded Microbial Friends & Foes REU; and information for current Cornell students on CIHMID’s URE.
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Opportunistic infections at the host-pathogen interface
Opportunistic pathogens can subvert infection barriers (e.g., host immune functions and nutrient limitations) and switch from peaceful commensal to potentially lethal pathogen. The factors promoting either outcome are unknown, but must be shaped by dynamic physiological interactions between host and pathogen. This project aims to determine key factors at the host-pathogen interface that mediate the […]
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Esther Angert
Our research explores the impact of host behavior and nutritional needs on the evolution of intestinal symbionts. Current projects include the study of signals that coordinate the physiology and development of intestinal bacteria with the feeding activity of their host. We are also interested in[...]